I recently reconstructed a relative’s genome using DNA Genics DNA Kit Studio. I had previously reconstructed this individual’s genome using the Borland Genetics suite, but the results I get here are wildly different.
For a start, this kit almost consistently scores 4-6% Subsaharan and/or Northeast African (Horner). This would translate roughly to one black great-great grandparent, something I KNOW this particular person does not have. The other kits used in the reconstruction process, by the way, score close to zero SSA. Here is this individual’s Eurogenes K13:
1 | North_Atlantic | 42.52 |
2 | Baltic | 20.58 |
3 | West_Asian | 10.8 |
4 | West_Med | 10.18 |
5 | Northeast_African | 4.3 |
6 | East_Med | 3.33 |
7 | Oceanian | 3.05 |
8 | Siberian | 2.6 |
9 | South_Asian | 1.67 |
10 | Sub-Saharan | 0.57 |
11 | Amerindian | 0.39 |
In additon to the SSA being well overstated, it also seems to conflate any Southern Indian ancestry with Oceanian, a problem also encountered with the Borland superkit. This person I would expect to have around 2-3% South Asian. Other than that, it seems quite consistent with what I know of this person’s pedigree.
I also reconstructed the genome of someone a bit further back and, while it is obviously incomplete, it seems accurate enough for the bulk of this person’s ancestry. From this I was able to reconstruct yet another genome and, well, the excess SSA struck again. Obviously this isn’t so much the program as it is the limited amount of the person’s actual genome being reconstructed.